Ontology highlight
ABSTRACT:
SUBMITTER: Heger P
PROVIDER: S-EPMC7535936 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
eLife 20200716
The Cambrian explosion was a unique animal radiation ~540 million years ago that produced the full range of body plans across bilaterians. The genetic mechanisms underlying these events are unknown, leaving a fundamental question in evolutionary biology unanswered. Using large-scale comparative genomics and advanced orthology evaluation techniques, we identified 157 bilaterian-specific genes. They include the entire Nodal pathway, a key regulator of mesoderm development and left-right axis speci ...[more]