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Beyond cardiovascular medicine: potential future uses of icosapent ethyl.


ABSTRACT: The REDUCE-IT trial demonstrated that icosapent ethyl, an ethyl ester of eicosapentaenoic acid (EPA), reduced cardiovascular events in an at-risk population by a substantial degree. While the cardiovascular protective properties of this compound are now proven, several other potential uses are being actively explored in clinical studies. These areas of investigation include cancer, inflammatory bowel disease, infections, Alzheimer's disease, dementia, and depression. The next decade promises to deepen our understanding of the beneficial effects that EPA may offer beyond cardiovascular risk reduction.

SUBMITTER: Bhatt DL 

PROVIDER: S-EPMC7537800 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Beyond cardiovascular medicine: potential future uses of icosapent ethyl.

Bhatt Deepak L DL   Hull Mark A MA   Song Mingyang M   Van Hulle Carol C   Carlsson Cindy C   Chapman M John MJ   Toth Peter P PP  

European heart journal supplements : journal of the European Society of Cardiology 20201006 Suppl J


The REDUCE-IT trial demonstrated that icosapent ethyl, an ethyl ester of eicosapentaenoic acid (EPA), reduced cardiovascular events in an at-risk population by a substantial degree. While the cardiovascular protective properties of this compound are now proven, several other potential uses are being actively explored in clinical studies. These areas of investigation include cancer, inflammatory bowel disease, infections, Alzheimer's disease, dementia, and depression. The next decade promises to  ...[more]

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