Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC7538541 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in endocrinology 20200923
Obesity has become a global health issue, but effective therapies remain very limited. Adaptive thermogenesis promotes weight loss by dissipating energy in the form of heat, thereby representing a promising target to counteract obesity. Notably, the regulation of thermogenesis is tightly orchestrated by complex neuronal networks, especially those in the hypothalamus. Recent evidence highlights the importance of adenosine monophosphate-activated protein kinase (AMPK) within the ventromedial nucle ...[more]