ABSTRACT: Background Perceived stress, burnout, and poor sleep quality are high among medical students. Interventions designed to target these issues are necessary to promote the health and well-being of medical students. The purpose of this study was twofold: 1) to assess the feasibility of implementing a sunrise alarm clock intervention with medical students and 2) to evaluate the impact of the intervention on perceived stress, burnout scores, and sleep quality. Methods We conducted a feasibility study to evaluate the efficacy of a two-week, sunrise alarm clock intervention in combination with electronic device removal at bedtime. We assessed first- and second-year medical students’ perceived stress, burnout scores, including Emotional Exhaustion, Depersonalization, and Low Sense of Personal Achievement, and sleep quality before and after the intervention. In addition, we measured smartphone addiction prior to the intervention. Results A total of 57 students consented to participate, of which 55 completed both the pre- and post-assessments (3.5% attrition). The mean age of the participants was 24.8?±?1.9?years, 50.9% (n =?29) identified as women, and 68.4% (n =?39) identified as white. Pre-intervention, 42.1% (n =?24) of students met criteria for smartphone addiction and 77.2% (n =?44) met criteria for poor sleep quality. In addition, 22.8% (n =?13) of participants had high emotional exhaustion, 64.9% (n =?31) high depersonalization, and 42.1% (n =?24) low sense of personal accomplishment prior to the intervention. Following the two-week intervention, participants showed improvements in emotional exhaustion (p =?0.001, Cohen’s d?=?0.353), depersonalization (p?=?0.001, Cohen’s d?=?0.411) low sense of personal accomplishment (p =?0.023, Cohen’s d?=?0.275), perceived stress (p