Ontology highlight
ABSTRACT:
SUBMITTER: Joaquim M
PROVIDER: S-EPMC7539839 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Joaquim Mariana M Escobar-Henriques Mafalda M
Frontiers in cell and developmental biology 20200922
Mitochondria entail an incredible dynamism in their morphology, impacting death signaling and selective elimination of the damaged organelles. In turn, by recycling the superfluous or malfunctioning mitochondria, mostly prevalent during aging, mitophagy contributes to maintain a healthy mitochondrial network. Mitofusins locate at the outer mitochondrial membrane and control the plastic behavior of mitochondria, by mediating fusion events. Besides deciding on mitochondrial interconnectivity, mito ...[more]