A data-driven prospective study of dementia among older adults in the United States.

ABSTRACT:

Background

Studies examining risk factors for dementia have typically focused on testing a priori hypotheses within specific risk factor domains, leaving unanswered the question of what risk factors across broad and diverse research fields may be most important to predicting dementia. We examined the relative importance of 65 sociodemographic, early-life, economic, health and behavioral, social, and genetic risk factors across the life course in predicting incident dementia and how these rankings may vary across racial/ethnic (non-Hispanic white and black) and gender (men and women) groups.

Methods and findings

We conducted a prospective analysis of dementia and its association with 65 risk factors in a sample of 7,908 adults aged 51 years and older from the nationally repre

SUBMITTER: Weiss J 

PROVIDER: S-EPMC7540891 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature