Ontology highlight
ABSTRACT:
SUBMITTER: Kamat V
PROVIDER: S-EPMC7542836 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Kamat Vinuta V Santosh Rangappa R Poojary Boja B Nayak Suresh P SP Kumar Banoth Karan BK Sankaranarayanan Murugesan M Faheem Khanapure Sheela S Barretto Delicia Avilla DA Vootla Shyam K SK
ACS omega 20200925 39
A new class of compounds formed by the linkage of -C(O)-NH- with pyridine and thiazole moieties was designed, synthesized, and characterized by various spectral approaches. The newly characterized compounds were evaluated for their antimicrobial as well as anti-inflammatory properties. The <i>in vitro</i> anti-inflammatory activity of these compounds was evaluated by denaturation of the bovine serum albumin method and showed inhibition in the range of IC<sub>50</sub> values-46.29-100.60 μg/mL. A ...[more]