Ontology highlight
ABSTRACT:
SUBMITTER: Shen J
PROVIDER: S-EPMC7543192 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Shen Jun J Chen Xiao-Chang XC Li Wang-Jun WJ Han Qiu Q Chen Chun C Lu Jing-Min JM Zheng Jin-Yu JY Xue Shou-Ru SR
The Journal of international medical research 20201001 10
<h4>Objective</h4>To identify Parkinson's disease (PD)-associated deregulated pathways and genes, to further elucidate the pathogenesis of PD.<h4>Methods</h4>Dataset GSE100054 was downloaded from the Gene Expression Omnibus, and differentially expressed genes (DEGs) in PD samples were identified. Functional enrichment analyses were conducted for the DEGs. The top 10 hub genes in the protein-protein interaction (PPI) network were screened out and used to construct a support vector machine (SVM) m ...[more]