Unknown

Dataset Information

0

Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review.


ABSTRACT: Patchouli alcohol (PA), a tricyclic sesquiterpene, is a dominant bioactive component in oil extracted from the aerial parts of Pogostemon cablin (patchouli). Diverse beneficial activities have been reported, including anti-influenza virus, anti-depressant, anti-nociceptive, vasorelaxation, lung protection, brain protection, anti-ulcerogenic, anti-colitis, pre-biotic-like, anti-inflammatory, anti-cancer and protective activities against metabolic diseases. However, detailed mechanistic studies are required to explore the possibility of developing PA as a functional food material or promising drug for the prevention and treatment of human diseases. This review highlights multiple molecular targets and working mechanisms by which PA mediates health benefits.

SUBMITTER: Lee HS 

PROVIDER: S-EPMC7543893 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review.

Lee Hee-Seop HS   Lee Jihye J   Smolensky Dmitriy D   Lee Seong-Ho SH  

International immunopharmacology 20201008 Pt A


Patchouli alcohol (PA), a tricyclic sesquiterpene, is a dominant bioactive component in oil extracted from the aerial parts of Pogostemon cablin (patchouli). Diverse beneficial activities have been reported, including anti-influenza virus, anti-depressant, anti-nociceptive, vasorelaxation, lung protection, brain protection, anti-ulcerogenic, anti-colitis, pre-biotic-like, anti-inflammatory, anti-cancer and protective activities against metabolic diseases. However, detailed mechanistic studies ar  ...[more]

Similar Datasets

| S-EPMC7606100 | biostudies-literature
| S-EPMC2946303 | biostudies-literature
| S-EPMC7221186 | biostudies-literature
| S-EPMC3492348 | biostudies-literature
| S-EPMC8439377 | biostudies-literature
| S-EPMC6264369 | biostudies-literature
| S-EPMC6928788 | biostudies-literature
| S-EPMC6358731 | biostudies-literature
| S-EPMC8403477 | biostudies-literature
| S-EPMC8206506 | biostudies-literature