Rewiring of gene expression in circulating white blood cells is associated with pregnancy outcome in heifers (Bos taurus).
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ABSTRACT:
SUBMITTER: Moorey SE
PROVIDER: S-EPMC7544915 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Rewiring of gene expression in circulating white blood cells is associated with pregnancy outcome in heifers (Bos taurus).
Moorey Sarah E SE Walker Bailey N BN Elmore Michelle F MF Elmore Joshua B JB Rodning Soren P SP Biase Fernando H FH
Scientific reports 20201008 1
Infertility is a challenging phenomenon in cattle that reduces the sustainability of beef production worldwide. Here, we tested the hypothesis that gene expression profiles of protein-coding genes expressed in peripheral white blood cells (PWBCs), and circulating micro RNAs in plasma, are associated with female fertility, measured by pregnancy outcome. We drew blood samples from 17 heifers on the day of artificial insemination and analyzed transcript abundance for 10,496 genes in PWBCs and 290 c ...[more]
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