Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Z
PROVIDER: S-EPMC7544984 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhou Zhixia Z Gong Qi Q Lin Zhijuan Z Wang Yin Y Li Mengkun M Wang Lu L Ding Hongfei H Li Peifeng P
Frontiers in oncology 20200925
Ser/Arg-rich (SR) proteins are RNA-binding proteins known as constitutive and alternative splicing (AS) regulators that regulate multiple aspects of the gene expression program. Ser/Arg-rich splicing factor 3 (SRSF3) is the smallest member of the SR protein family, and its level is controlled by multiple factors and involves complex mechanisms in eukaryote cells, whereas the aberrant expression of SRSF3 is associated with many human diseases, including cancer. Here, we review state-of-the-art re ...[more]