Ontology highlight
ABSTRACT:
SUBMITTER: Stietz MS
PROVIDER: S-EPMC7545191 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Stietz Maria Silvina MS Liang Xiaoye X Li Hao H Zhang Xinran X Dong Tao G TG
Nature communications 20201008 1
The type VI protein secretion system (T6SS) is a powerful needle-like machinery found in Gram-negative bacteria that can penetrate the cytosol of receiving cells in milliseconds by physical force. Anchored by its membrane-spanning complex (MC) and a baseplate (BP), the T6SS sheath-tube is assembled in a stepwise process primed by TssA and terminated by TagA. However, the molecular details of its assembly remain elusive. Here, we systematically examined the initiation and termination of contracti ...[more]