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MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders.


ABSTRACT: The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in neurodevelopmental, cognitive, and behavioral disorders.

SUBMITTER: Smith M 

PROVIDER: S-EPMC7545264 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders.

Smith Moyra M  

Frontiers in molecular biosciences 20200925


The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in n  ...[more]

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