Ontology highlight
ABSTRACT:
SUBMITTER: Tong ZB
PROVIDER: S-EPMC7545370 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Tong Ze-Bin ZB Ai Hua-Song HS Li Jia-Bin JB
Frontiers in cell and developmental biology 20200925
DNA packs into highly condensed chromatin to organize the genome in eukaryotes but occludes many regulatory DNA elements. Access to DNA within nucleosomes is therefore required for a variety of biological processes in cells including transcription, replication, and DNA repair. To cope with this problem, cells employ a set of specialized ATP-dependent chromatin-remodeling protein complexes to enable dynamic access to packaged DNA. In the present review, we summarize the recent advances in the fun ...[more]