Ontology highlight
ABSTRACT:
SUBMITTER: van de Ven K
PROVIDER: S-EPMC7547016 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
van de Ven Koen K de Heij Femke F van Dijken Harry H Ferreira José A JA de Jonge Jørgen J
Communications biology 20201009 1
Traditional influenza vaccines primarily induce a narrow antibody response that offers no protection against heterosubtypic infections. Murine studies have shown that T cells can protect against a broad range of influenza strains. However, ferrets are a more potent model for studying immune correlates of protection in influenza infection. We therefore set out to investigate the role of systemic and respiratory T cells in the protection against heterosubtypic influenza A infections in ferrets. H1 ...[more]