Ontology highlight
ABSTRACT:
SUBMITTER: Van den Broeck F
PROVIDER: S-EPMC7547230 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Van den Broeck Frederik F Savill Nicholas J NJ Imamura Hideo H Sanders Mandy M Maes Ilse I Cooper Sinclair S Mateus David D Jara Marlene M Adaui Vanessa V Arevalo Jorge J Llanos-Cuentas Alejandro A Garcia Lineth L Cupolillo Elisa E Miles Michael M Berriman Matthew M Schnaufer Achim A Cotton James A JA Dujardin Jean-Claude JC
Proceedings of the National Academy of Sciences of the United States of America 20200921 40
The tropical Andes are an important natural laboratory to understand speciation in many taxa. Here we examined the evolutionary history of parasites of the <i>Leishmania braziliensis</i> species complex based on whole-genome sequencing of 67 isolates from 47 localities in Peru. We first show the origin of Andean <i>Leishmania</i> as a clade of near-clonal lineages that diverged from admixed Amazonian ancestors, accompanied by a significant reduction in genome diversity and large structural varia ...[more]