Ontology highlight
ABSTRACT:
SUBMITTER: Basalay MV
PROVIDER: S-EPMC7547701 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Basalay Maryna V MV Wiart Marlene M Chauveau Fabien F Dumot Chloe C Leon Christelle C Amaz Camille C Bolbos Radu R Cash Diana D Kim Eugene E Mechtouff Laura L Cho Tae-Hee TH Nighoghossian Norbert N Davidson Sean M SM Ovize Michel M Yellon Derek M DM
Scientific reports 20201009 1
Reperfusion is the only existing strategy for patients with acute ischemic stroke, however it causes further brain damage itself. A feasible therapy targeting reperfusion injury is remote ischemic conditioning (RIC). This was a two-centre, randomized, blinded international study, using translational imaging endpoints, aimed to examine the neuroprotective effects of RIC in ischemic stroke model. 80 male rats underwent 90-min middle cerebral artery occlusion. RIC consisted of 4 × 5 min cycles of l ...[more]