Potential miRNAs for miRNA-Based Therapeutics in Breast Cancer.
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ABSTRACT:
SUBMITTER: Wong JS
PROVIDER: S-EPMC7549352 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
Potential miRNAs for miRNA-Based Therapeutics in Breast Cancer.
Wong Jun Sheng JS Cheah Yoke Kqueen YK
Non-coding RNA 20200713 3
MicroRNAs (miRNAs) are small non-coding RNAs that can post-transcriptionally regulate the genes involved in critical cellular processes. The aberrant expressions of oncogenic or tumor suppressor miRNAs have been associated with cancer progression and malignancies. This resulted in the dysregulation of signaling pathways involved in cell proliferation, apoptosis and survival, metastasis, cancer recurrence and chemoresistance. In this review, we will first (i) provide an overview of the miRNA biog ...[more]
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