Ontology highlight
ABSTRACT:
SUBMITTER: Deng M
PROVIDER: S-EPMC7549573 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Deng Mingzhu M Liu Chen C Jiang Weiqing W Wang Fei F Zhou Juan J Wang Dong D Wang Yonggang Y
Molecular genetics & genomic medicine 20200822 10
<h4>Background</h4>Benign paroxysmal positional vertigo (BPPV) is a common, self-limited, and favorable prognostic peripheral vestibular disorder. BPPV is transmitted in an autosomal dominant fashion, but most cases occur sporadically. Little research has been reported regarding the mutation spectrum of sporadic BPPV in a large cohort. This study attempted to identify the causative candidate variants associated with BPPV in VDR, LOXL1, and LOXL1-AS1.<h4>Methods</h4>An amplicon-targeted next-gene ...[more]