Ontology highlight
ABSTRACT:
SUBMITTER: Wolf J
PROVIDER: S-EPMC7550331 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Wolf Julian J Auw-Haedrich Claudia C Schlecht Anja A Boneva Stefaniya S Mittelviefhaus Hans H Lapp Thabo T Agostini Hansjürgen H Reinhard Thomas T Schlunck Günther G Lange Clemens A K CAK
Scientific reports 20201012 1
This study characterizes the transcriptome and the cellular tumor microenvironment (TME) of conjunctival melanoma (CM) and identifies prognostically relevant biomarkers. 12 formalin-fixed and paraffin-embedded CM were analyzed by MACE RNA sequencing, including six cases each with good or poor clinical outcome, the latter being defined by local recurrence and/or systemic metastases. Eight healthy conjunctival specimens served as controls. The TME of CM, as determined by bioinformatic cell type en ...[more]