Ontology highlight
ABSTRACT:
SUBMITTER: Durhuus JA
PROVIDER: S-EPMC7550337 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Durhuus Jon Ambæk JA Hansson Svenja S Morville Thomas T Kuhlman Anja Birk AB Dohlmann Tine Lovsø TL Larsen Steen S Helge Jørn Wulff JW Angleys Maria M Muniesa-Vargas Alba A Bundgaard Jens R JR Hickson Ian David ID Dela Flemming F Desler Claus C Rasmussen Lene Juel LJ
Scientific reports 20201012 1
Statins are prescribed to treat hypercholesterolemia and to reduce the risk of cardiovascular disease. However, statin users frequently report myalgia, which can discourage physical activity or cause patients to discontinue statin use, negating the potential benefit of the treatment. Although a proposed mechanism responsible for Statin-Associated Myopathy (SAM) suggests a correlation with impairment of mitochondrial function, the relationship is still poorly understood. Here, we provide evidence ...[more]