Prognostic value of transient conduction disturbance in out-of-hospital cardiac arrest.

ABSTRACT: Aim:A retrospective observational study to verify the impact of electrocardiograms (ECGs) following out-of-hospital cardiac arrest (OHCA) on mortality. Methods:We retrospectively studied 101 OHCA patients who achieved a return of spontaneous circulation (ROSC) and survived for ?3 h. Among them, 50 patients (66 ± 17 years; 22 male) were evaluated using 12-lead ECGs repeatedly and were included in the final analysis: immediately after ROSC (initial ECG) and after the initial evaluation in the emergency department (second ECG). Transient conduction disturbance (transient CD) was defined as a narrowing in QRS duration from the initial to second ECG of ?18 ms. Multivariate Cox regression analyses were carried out to predict 90-day mortality following OHCA. Results:Among 50 OHCA patients, 30 patients survived for 90 days. Thirty patients had initial ventricular fibrillation rhythm. Median emergency medical services response time and low-flow duration were 8 and 21 min, respectively. Multivariate analysis showed that the transient CD and low-flow duration were significant predictors of all-cause mortality (hazard ratio 16.55, 1.06; P = 0.001, 0.022, respectively). Conclusion:Transient CD is a powerful predictor of 90-day mortality in patients who survived 3 h after ROSC from OHCA.

SUBMITTER: Iiya M 

PROVIDER: S-EPMC7550558 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature