Ontology highlight
ABSTRACT:
SUBMITTER: Kang D
PROVIDER: S-EPMC7550586 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Scientific reports 20201012 1
Cep215 (also known as Cdk5rap2) is a centrosome protein which is involved in microtubule organization. Cep215 is also placed at specific subcellular locations and organizes microtubules outside the centrosome. Here, we report that Cep215 is involved in morphological differentiation of astrocytes. Cep215 was specifically localized at the glial processes as well as centrosomes in developing astrocytes. Morphological differentiation of astrocytes was suppressed in the Cep215-deleted P19 cells and i ...[more]