Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC7550983 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Li Rongrong R Wu Huan H Jiang Huiyang H Wang Qiuman Q Dou Zhiyuan Z Ma Hanlin H Yan Shi S Yuan Cunzhong C Yang Ning N Kong Beihua B
Oncology reports 20200903 5
High-grade serous ovarian carcinoma (HGSOC) is one of the most lethal gynecological malignancies; however, the precise molecular mechanisms have not been fully characterized. Fibulin‑5 (FBLN‑5) is an extracellular matrix (ECM) glycoprotein, and plays a crucial role in maintaining the stability of ECM structures, regulating cell proliferation and tumorigenesis. In the present study, the expression of FBLN‑5, as determined by western blot analysis and immunohistochemistry, was significantly increa ...[more]