Ontology highlight
ABSTRACT:
SUBMITTER: Biolchi AM
PROVIDER: S-EPMC7551070 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Biolchi Andréia Mayer AM de Oliveira Danilo Gustavo Rodrigues DGR Amaral Henrique de Oliveira HO Campos Gabriel Avohay Alves GAA Gonçalves Jacqueline Coimbra JC de Souza Adolfo Carlos Barros ACB Lima Marcos Robalinho MR Silva Luciano Paulino LP Mortari Márcia Renata MR
Toxins 20200827 9
Parkinson's disease (PD) is a progressive neurodegenerative condition that affects the Central Nervous System (CNS). Insect venoms show high molecular variability and selectivity in the CNS of mammals and present potential for the development of new drugs for the treatment of PD. In this study, we isolated and identified a component of the venom of the social wasp <i>Parachartergus fraternus</i> and evaluated its neuroprotective activity in the murine model of PD. For this purpose, the venom was ...[more]