Ontology highlight
ABSTRACT:
SUBMITTER: Dadar M
PROVIDER: S-EPMC7552231 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Dadar Mahsa M Camicioli Richard R Duchesne Simon S Collins D Louis DL
Alzheimer's & dementia (Amsterdam, Netherlands) 20201013 1
<h4>Introduction</h4>Cognitive decline in Alzheimer's disease is associated with amyloid beta (Aβ) accumulation, neurodegeneration, and cerebral small vessel disease, but the temporal relationships among these factors is not well established.<h4>Methods</h4>Data included white matter hyperintensity (WMH) load, gray matter (GM) atrophy and Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS13) scores for 720 participants and cerebrospinal fluid amyloid (Aβ1-42) for 461 participants from the ...[more]