Reliability of the Mouse Grimace Scale in C57BL/6JRj Mice.
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ABSTRACT:
SUBMITTER: Hohlbaum K
PROVIDER: S-EPMC7552260 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Reliability of the Mouse Grimace Scale in C57BL/6JRj Mice.
Hohlbaum Katharina K Corte Giuliano Mario GM Humpenöder Melanie M Merle Roswitha R Thöne-Reineke Christa C
Animals : an open access journal from MDPI 20200914 9
To maintain and foster the welfare of laboratory mice, tools that reliably measure the current state of the animals are applied in clinical assessment. One of these is the Mouse Grimace Scale (MGS), a coding system for facial expression analysis. Since there are concerns about the objectivity of the MGS, we further investigated its reliability. Four observers (two experienced and two inexperienced in use of the MGS) scored 188 images of 33 female and 31 male C57BL/6JRj mice. Images were generate ...[more]
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