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Trajectories of vital status parameters and risk of mortality among acute organophosphorus poisoning patients - a latent class growth analysis.


ABSTRACT: BACKGROUND:Acute organophosphorus (OP) poisoning is one of the major causes of mortality among patients presenting to emergency departments in developing countries. Although various predictors of mortality among OP poisoning patients have been identified, the role of repeated measurements of vital signs in determining the risk of mortality is not yet clear. Therefore, the present study examined the relationship between trajectories of vital signs and mortality among OP poisoning patients using latent class growth analysis (LCGA). METHODS:This was a retrospective cohort study using data for 449 OP poisoning patients admitted to Civil-Hospital Karachi from Aug'10 to Sep'16. Demographic data and vital signs, including body temperature, blood pressure, heart rate, respiratory rate, and partial-oxygen pressure, were retrieved from medical records. The trajectories of vital signs were formed using LCGA, and these trajectories were applied as independent variables to determine the risk of mortality using Cox-proportional hazards models. P-values of

SUBMITTER: Farooqui WA 

PROVIDER: S-EPMC7552362 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Trajectories of vital status parameters and risk of mortality among acute organophosphorus poisoning patients - a latent class growth analysis.

Farooqui Waqas Ahmed WA   Uddin Mudassir M   Qadeer Rashid R   Shafique Kashif K  

BMC public health 20201012 1


<h4>Background</h4>Acute organophosphorus (OP) poisoning is one of the major causes of mortality among patients presenting to emergency departments in developing countries. Although various predictors of mortality among OP poisoning patients have been identified, the role of repeated measurements of vital signs in determining the risk of mortality is not yet clear. Therefore, the present study examined the relationship between trajectories of vital signs and mortality among OP poisoning patients  ...[more]

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