Ontology highlight
ABSTRACT:
SUBMITTER: Shayan M
PROVIDER: S-EPMC7552602 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Shayan Mahdis M Huang Ngan F NF
Bioengineering (Basel, Switzerland) 20200820 3
Extensive damage to skeletal muscle tissue due to volumetric muscle loss (VML) is beyond the inherent regenerative capacity of the body, and results in permanent functional debilitation. Current clinical treatments fail to fully restore native muscle function. Recently, cell-based therapies have emerged as a promising approach to promote skeletal muscle regeneration following injury and/or disease. Stem cell populations, such as muscle stem cells, mesenchymal stem cells and induced pluripotent s ...[more]