Ontology highlight
ABSTRACT:
SUBMITTER: Buchholz T
PROVIDER: S-EPMC7552603 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Buchholz Tim T Hildebrand Maria M Heider Anja A Stenger Valentina V Arens Daniel D Spadavecchia Claudia C Zeiter Stephan S
Animals : an open access journal from MDPI 20200917 9
When using animals in biomedical research, investigators have the responsibility to ensure adequate analgesia. Currently, transdermal fentanyl patches (TFP) are often used to provide postoperative analgesia in large laboratory animals. The aim of this study was to compare the fentanyl uptake resulting from TFP applied at two different locations, namely the foreleg and the thorax, in healthy adult sheep. Twelve sheep received a TFP with an intended dosage of 2 ug/kg/h. Blood samples were taken at ...[more]