Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering.
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ABSTRACT:
SUBMITTER: Marrazzo P
PROVIDER: S-EPMC7552777 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering.
Marrazzo Pasquale P O'Leary Cian C
Bioengineering (Basel, Switzerland) 20200902 3
Although a large panel of natural antioxidants demonstrate a protective effect in preventing cellular oxidative stress, their low bioavailability limits therapeutic activity at the targeted injury site. The importance to deliver drug or cells into oxidative microenvironments can be realized with the development of biocompatible redox-modulating materials. The incorporation of antioxidant compounds within implanted biomaterials should be able to retain the antioxidant activity, while also allowin ...[more]
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