Prostate cancer risk prediction using a polygenic risk score.
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ABSTRACT:
SUBMITTER: Sipeky C
PROVIDER: S-EPMC7553910 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Prostate cancer risk prediction using a polygenic risk score.
Sipeky Csilla C Talala Kirsi M KM Tammela Teuvo L J TLJ Taari Kimmo K Auvinen Anssi A Schleutker Johanna J
Scientific reports 20201013 1
Hereditary factors have a strong influence on prostate cancer (PC) risk and poorer outcomes, thus stratification by genetic factors addresses a critical need for targeted PC screening and risk-adapted follow-up. In this Finnish population-based retrospective study 2283 clinically diagnosed and 455 screen-detected patients from the Finnish Randomised Study of Screening for Prostate Cancer (FinRSPC), 2400 healthy individuals have been involved. Individual genetic risk through establishment of a po ...[more]
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