Ontology highlight
ABSTRACT:
SUBMITTER: Dausset C
PROVIDER: S-EPMC7553951 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Dausset Caroline C Bornes Stéphanie S Miquel Sylvie S Kondjoyan Nathalie N Angenieux Magaly M Nakusi Laurence L Veisseire Philippe P Alaterre Elina E Bermúdez-Humarán Luis G LG Langella Philippe P Engel Erwan E Forestier Christiane C Nivoliez Adrien A
Scientific reports 20201013 1
GYNOPHILUS (Lcr REGENERANS) is a live biotherapeutic product (LBP) aimed at restoring the vaginal microbiome and contains the live biotherapeutic microorganism Lactobacillus rhamnosus Lcr35. In this study, the LBP formulation and manufacturing process significantly enhanced the anti-Candida activity of L. rhamnosus Lcr35, with a complete loss of viability of the yeast after 48 h of coincubation. Sodium thiosulfate (STS), one excipient of the product, was used as a potentiator of the anti-Candida ...[more]