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A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery.

ABSTRACT: A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

SUBMITTER: Uraguchi K 

PROVIDER: S-EPMC7554319 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery.

Uraguchi Kensuke K   Kozakura Kenichi K   Oka Satoshi S   Higaki Takaya T   Makihara Seiichiro S   Imai Toshi T   Doi Akira A   Ohta Tsuyoshi T   Kariya Shin S   Nishizaki Kazunori K  

Medical mycology case reports 20200925

A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findin  ...[more]

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