Ontology highlight
ABSTRACT:
SUBMITTER: Kovaleva O
PROVIDER: S-EPMC7554830 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kovaleva Olga O Podlesnaya Polina P Rashidova Madina M Samoilova Daria D Petrenko Anatoly A Zborovskaya Irina I Mochalnikova Valeria V Kataev Vladimir V Khlopko Yuri Y Plotnikov Andrey A Gratchev Alexei A
Biomedicines 20200913 9
The link between a lung tumor and the lung microbiome is a largely unexplored issue. To investigate the relationship between a lung microbiome and the phenotype of an inflammatory stromal infiltrate, we studied a cohort of 89 patients with non-small cell lung cancer. The microbiome was analyzed in tumor and adjacent normal tissue by 16S rRNA amplicon sequencing. Characterization of the tumor stroma was done using immunohistochemistry. We demonstrated that the bacterial load was higher in adjacen ...[more]