Ontology highlight
ABSTRACT:
SUBMITTER: Racis M
PROVIDER: S-EPMC7554836 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Racis Milena M Stanisławska-Sachadyn Anna A Sobiczewski Wojciech W Wirtwein Marcin M Krzemiński Michał M Krawczyńska Natalia N Limon Janusz J Rynkiewicz Andrzej A Rynkiewicz Andrzej A Gruchała Marcin M
Life (Basel, Switzerland) 20200918 9
Oxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (<i>PON1</i> c.575A>G, <i>MPO</i> c.-463G>A, <i>SOD2</i> c.47T>C, <i>GCLM</i> c.-590C>T, <i>NOS3</i> c.894G>T, <i>NOS3</i> c.-786T>C, <i>CYBA</i> c.214C>T, and <i>CYBA</i> c.-932A>G) and assessed the extent of atherosclerosis in coronary arteries based on Gensini s ...[more]