Ontology highlight
ABSTRACT:
SUBMITTER: Battelli MG
PROVIDER: S-EPMC7555004 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Battelli Maria Giulia MG Bortolotti Massimo M Bolognesi Andrea A Polito Letizia L
Antioxidants (Basel, Switzerland) 20200908 9
The senescence process is the result of a series of factors that start from the genetic constitution interacting with epigenetic modifications induced by endogenous and environmental causes and that lead to a progressive deterioration at the cellular and functional levels. One of the main causes of aging is oxidative stress deriving from the imbalance between the production of reactive oxygen (ROS) and nitrogen (RNS) species and their scavenging through antioxidants. Xanthine oxidoreductase (XOR ...[more]