Ontology highlight
ABSTRACT:
SUBMITTER: Deshpande D
PROVIDER: S-EPMC7555347 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Deshpande Dhruva D Grieshober Mark M Wondany Fanny F Gerbl Fabian F Noschka Reiner R Michaelis Jens J Stenger Steffen S
International journal of molecular sciences 20200914 18
The antimicrobial peptide LL-37 inhibits the growth of the major human pathogen <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>), but the mechanism of the peptide-pathogen interaction inside human macrophages remains unclear. Super-resolution imaging techniques provide a novel opportunity to visualize these interactions on a molecular level. Here, we adapt the super-resolution technique of stimulated emission depletion (STED) microscopy to study the uptake, intracellular localization and interacti ...[more]