Ontology highlight
ABSTRACT:
SUBMITTER: Okuliarova M
PROVIDER: S-EPMC7555372 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Okuliarova Monika M Rumanova Valentina Sophia VS Stebelova Katarina K Zeman Michal M
International journal of molecular sciences 20200921 18
Dim light at night (dLAN) is associated with metabolic risk but the specific effects on lipid metabolism have only been evaluated to a limited extent. Therefore, to explore whether dLAN can compromise lipid metabolic homeostasis in healthy individuals, we exposed Wistar rats to dLAN (~2 lx) for 2 and 5 weeks and analyzed the main lipogenic pathways in the liver and epididymal fat pad, including the control mechanisms at the hormonal and molecular level. We found that dLAN promoted hepatic triacy ...[more]