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Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?

ABSTRACT: As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in those with multiple cardiovascular risk factors such as cancer, diabetes, obesity and hypertension. In this review, we will examine the cardiac involvement associated with SARS-CoV-2 infection, focusing on the pathophysiological mechanism underlying manifestations and their clinical implication, taking into account the main scientific papers published to date.

SUBMITTER: Mottola FF

PROVIDER: S-EPMC7555654 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?

Mottola Filiberto Fausto FF Verde Nicoletta N Ricciolino Riccardo R Di Mauro Marco Di MD Migliaccio Marco Giuseppe MG Carfora Vincenzo V Spiniello Giorgio G Coppola Nicola N Vanvitelli Covid-Group

Life (Basel, Switzerland) 20200827 9

As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in tho ...[more]

PMID: 32867137

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