Ontology highlight
ABSTRACT:
SUBMITTER: Pucci M
PROVIDER: S-EPMC7555671 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Foods (Basel, Switzerland) 20200914 9
Lemon essential oil (LEO) is a well-known flavoring agent with versatile biological activities. In the present study, we have isolated and characterized four citral-enriched fractions of winter LEO. We reported that in murine and human macrophages the pre-treatment with a mix of these fractions (Cfr-LEO) reduces the expression of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 induced by LPS. In addition, Cfr-LEO counteracts LPS-induced oxidative stress, as shown by the increase in the GSH ...[more]