Ontology highlight
ABSTRACT:
SUBMITTER: Wuertz-Kozak K
PROVIDER: S-EPMC7556040 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wuertz-Kozak Karin K Roszkowski Martin M Cambria Elena E Block Andrea A Kuhn Gisela A GA Abele Thea T Hitzl Wolfgang W Drießlein David D Müller Ralph R Rapp Michael A MA Mansuy Isabelle M IM Peters Eva M J EMJ Wippert Pia M PM
International journal of molecular sciences 20200910 18
Bone pathology is frequent in stressed individuals. A comprehensive examination of mechanisms linking life stress, depression and disturbed bone homeostasis is missing. In this translational study, mice exposed to early life stress (MSUS) were examined for bone microarchitecture (μCT), metabolism (qPCR/ELISA), and neuronal stress mediator expression (qPCR) and compared with a sample of depressive patients with or without early life stress by analyzing bone mineral density (BMD) (DXA) and metabol ...[more]