Ontology highlight
ABSTRACT:
SUBMITTER: Root DH
PROVIDER: S-EPMC7556367 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Root David H DH Barker David J DJ Estrin David J DJ Miranda-Barrientos Jorge A JA Liu Bing B Zhang Shiliang S Wang Hui-Ling HL Vautier Francois F Ramakrishnan Charu C Kim Yoon Seok YS Fenno Lief L Deisseroth Karl K Morales Marisela M
Cell reports 20200901 9
Ventral tegmental area (VTA) neurons play roles in reward and aversion. We recently discovered that the VTA has neurons that co-transmit glutamate and GABA (glutamate-GABA co-transmitting neurons), transmit glutamate without GABA (glutamate-transmitting neurons), or transmit GABA without glutamate (GABA-transmitting neurons). However, the functions of these VTA cell types in motivated behavior are unclear. To identify the functions of these VTA cell types, we combine recombinase mouse lines with ...[more]