Ontology highlight
ABSTRACT:
SUBMITTER: Shen B
PROVIDER: S-EPMC7560618 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Shen Bin B Zhou Pingping P Jiao Xue X Yao Zhen Z Ye Lidan L Yu Hongwei H
Nature communications 20201014 1
The diverse physiological functions of tocotrienols have listed them as valuable supplementations to α-tocopherol-dominated Vitamin E products. To make tocotrienols more readily available, tocotrienols-producing S. cerevisiae has been constructed by combining the heterologous genes from photosynthetic organisms with the endogenous shikimate pathway and mevalonate pathway. After identification and elimination of metabolic bottlenecks and enhancement of precursors supply, the engineered yeast can ...[more]