Impaired left amygdala resting state functional connectivity in subthreshold depression individuals.

ABSTRACT: Subthreshold depression (StD) affects people who experience clinically relevant depressive symptoms, which does not meet the diagnostic criteria for major depressive disorder (MDD). StD represents an ideal model for understanding the pathophysiological mechanisms of depression. Impaired emotion processing is a core feature of depression; careful investigation is required to better understand the neural correlates of emotion processing in depressed populations. In the current study, we explored whether the resting-state functional connectivity of the amygdala, a hub that taps a wide range of brain areas involved in emotion processing, is altered in individuals with StD when compared with healthy controls. Resting-state imaging data was collected from 59 individuals with StD and 59 age- and

SUBMITTER: Peng X 

PROVIDER: S-EPMC7560839 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature