In vivo estrogenicity of p-phenoxyphenol and p-pentyloxyphenol.
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ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC7560878 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
In vivo estrogenicity of p-phenoxyphenol and p-pentyloxyphenol.
Wang Yue Y Xiao Han H Yang Lei L Jia Xiaojing X Guo Xuan X Zhang Zhaobin Z
Scientific reports 20201014 1
p-Alkoxyphenols (AOPs) are a class of ethers that are widely used in industrial and agricultural productions and daily necessities. p-Phenoxyphenol (PhOP) and p-pentyloxyphenol (PeOP) belong to this class and have been reported to be estrogenic in vitro. However, their in vivo estrogenic activities have rarely been of concern. In this study, we performed an immature mouse uterotrophic assay and studied the estrogenic effects of these two compounds in mice. The results revealed that the uterine w ...[more]
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