Mast Cells in Skin Scarring: A Review of Animal and Human Research.
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ABSTRACT:
SUBMITTER: Ud-Din S
PROVIDER: S-EPMC7561364 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Mast Cells in Skin Scarring: A Review of Animal and Human Research.
Ud-Din Sara S Wilgus Traci A TA Bayat Ardeshir A
Frontiers in immunology 20200930
Mast cells (MCs) are an important immune cell type in the skin and play an active role during wound healing. MCs produce mediators that can enhance acute inflammation, stimulate re-epithelialisation as well as angiogenesis, and promote skin scarring. There is also a link between MCs and abnormal pathological cutaneous scarring, with increased numbers of MCs found in hypertrophic scars and keloid disease. However, there has been conflicting data regarding the specific role of MCs in scar formatio ...[more]
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