Ontology highlight
ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC7562924 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Li Zhe Z An Ran R Swetzig Wendy M WM Kanis Margaux M Nwani Nkechiyere N Turek John J Matei Daniela D Nolte David D
Scientific reports 20201015 1
Development of an assay to predict response to chemotherapy has remained an elusive goal in cancer research. We report a phenotypic chemosensitivity assay for epithelial ovarian cancer based on Doppler spectroscopy of infrared light scattered from intracellular motions in living three-dimensional tumor biopsy tissue measured in vitro. The study analyzed biospecimens from 20 human patients with epithelial ovarian cancer. Matched primary and metastatic tumor tissues were collected for 3 patients, ...[more]