Ontology highlight
ABSTRACT:
SUBMITTER: Matsuo K
PROVIDER: S-EPMC7563232 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Matsuo Koji K Tanabe Kazuhiro K Hayashi Masaru M Ikeda Masae M Yasaka Miwa M Machida Hiroko H Shida Masako M Sato Kenji K Yoshida Hiroshi H Hirasawa Takeshi T Imanishi Tadashi T Mikami Mikio M
Cancers 20200821 9
Comprehensive serum glycopeptide spectra analysis (CSGSA) evaluates >10,000 serum glycopeptides and identifies unique glycopeptide peaks and patterns via supervised orthogonal partial least-squares discriminant modeling. CSGSA was more accurate than cancer antigen 125 (CA125) or human epididymis protein 4 (HE4) for detecting early stage epithelial ovarian cancer. Combined CSGSA, CA125, and HE4 had improved diagnostic performance. Thus, CSGSA may be a useful screening tool for detecting early sta ...[more]