Ontology highlight
ABSTRACT:
SUBMITTER: Mutgan AC
PROVIDER: S-EPMC7563239 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Mutgan Ayse Ceren AC Jandl Katharina K Kwapiszewska Grazyna G
Cells 20200903 9
Pulmonary arterial hypertension (PAH) is a vascular disease that is characterized by elevated pulmonary arterial pressure (PAP) due to progressive vascular remodeling. Extracellular matrix (ECM) deposition in pulmonary arteries (PA) is one of the key features of vascular remodeling. Emerging evidence indicates that the basement membrane (BM), a specialized cluster of ECM proteins underlying the endothelium, may be actively involved in the progression of vascular remodeling. The BM and its steady ...[more]